NF1 and neurofibromatosis: Neurofibromatoses are a group of genetic disorders that affect nerve tissues. Neurofibromatosis is classified into neurofibromatosis type 1 (NF-1), neurofibromatosis type 2 (NF-2), and schwannomatosis, with NF-1 being the most prevalent and primarily impacting both the central and peripheral nervous systems.