Acetyl-ethyl extract from L. plantarum ATCC14917 and L. rhamnosus ATCC7469 exhibits targeted anti-colon cancer cell activity by inducing the intrinsic apoptosis pathway, downregulating the expression of anti-apoptotic genes Bcl-2 and Bcl-XL, and upregulating the expression of pro-apoptotic genes Bak, Bad, and Bax (9). Here, BCL2L1 is linked to malignant colon neoplasm.