YQYYHXBXD combined with biomedicine medicine can reduce the levels of serum sST2, galectin-3, LN, PIIIP, and serum IL-1β, TNF-α, hs-CRP, MMP-9, and other inflammatory factors in patients with CHF, and the degree of adverse reactions in the two groups was mild, which did not affect the clinical observations. This evidence concerns the gene IL1B and congestive heart failure.