Transforming growth factor β (TGF-β)/Smad signaling pathway, Wnt/β-catenin signaling pathway, vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF) and platelet-derived growth factor (PDGF) signaling pathways are currently the main focus of research on the pathophysiology and related treatment options of idiopathic pulmonary fibrosis at home and abroad (Claudia et al., 2020). The gene discussed is TGFB1; the disease is idiopathic pulmonary fibrosis.