Valosin-containing protein (VCP) disease, otherwise known as inclusion body myopathy (IBM) associated with Paget disease of the bone (PDB) and frontotemporal dementia (FTD) (frequently used acronym, IBMPFD), or more recently, multi-system proteinopathy type 1 (MSP1), is a progressive, debilitating, autosomal dominant genetic condition, which can affect the muscle, bone, and/or central nervous system. This evidence concerns the gene ATAD1 and frontotemporal dementia.