CYP27B1 and cystic fibrosis: Moreover, the family of genes including cytochrome P450 (CYP2R1, CYP27B1, CYP39 A1) and solute carriers (SLC10 A4, SLC16 A1, SLC16 A6, SLC30 A10, SLC39 A10) were upregulated, while ribosomal proteins (RPL10, RPL36 A, RPL39) were downregulated in the CM compared to the CF embryo groups (Table 2).