Two genes associated with testosterone in female UKBB participants were also associated with infertility risk (P < 1.00 × 10−3, Bonferroni adjustment for 50 unique genes): TRIM4 (F-ALL, burden test OR 1.03 (1.01–1.05), P = 4.05 × 10−4 across all variants with MAF <0.1%) and CYP3A43 (F-EXCL, burden test OR 1.02 (1.01–1.03), P = 4.84 × 10−4 across all variants with MAF <1%). The gene discussed is CYP3A43; the disease is Infertility.