As hormone dysregulation is central to many infertility diagnoses5,6, we conducted sex-specific GWAS meta-analyses of five reproductive hormones—follicle-stimulating hormone (FSH) (nfemale = 57,890, nmale = 6,095), luteinizing hormone (LH) (nfemale = 47,986, nmale = 6,769), estradiol (nfemale = 97,887, nmale = 39,165), progesterone (nfemale = 18,368) and total testosterone (nfemale = 246,862, nmale = 243,951)—collected at assessment center visits or identified through electronic health records, in six cohorts and publicly available summary statistics (Supplementary Table 9). This evidence concerns the gene PLOD1 and Infertility.