In the training set, there were statistically significant differences between the non-recurrence group and the recurrence group in terms of tumor invasion site (P = 0.001), tumor morphology (P<0.001), Knosp grading (P = 0.002), tumor resection range (P<0.001), immunohistochemical GH positivity (P = 0.004), and immunohistochemical PRL positivity (P = 0.036). This evidence concerns the gene PRL and neoplasm.