LGALS3 and amyotrophic lateral sclerosis: While GAL3 was identified as up-regulated in the muscle of mouse model of Duchenne muscular dystrophy [51, 52], amyotrophic lateral sclerosis [53], and merosin-deficient, lama2-related congenital muscular dystrophy [52], to date, GAL3 has not been identified as a biomarker in skeletal muscle-related diseases.