DMPK and myotonic dystrophy type 1: Stevanovski et al. (2022) further validated this approach, demonstrating hypermethylation in both full mutation and premutation carriers. Similarly, Rasmussen et al. (2022) discovered that in patients with Myotonic Dystrophy Type 1 (DM1), hypermethylation of CTG repeats was observed only in the full-penetrance allele of DMPK (with the shortest allele detected in the study having 142 repeats).