SERPIND1 and poisoning: Moreover, batroxobin exhibits significantly higher affinity for fibrin compared to thrombin and remains unaffected by antithromboprotein or heparin cofactor II inhibition, thereby promoting fiber adhesion.[10] According to the literature, microvascular thrombosis has been reported in patients with Bothrops moojeni poisoning.[17] When batroxobin is combined with other anticoagulant drugs for treating cerebral venous thrombosis, it can mitigate variations in coagulation index values caused by these drugs and prevent mutations in the coagulation system or bleeding events.