The literature primarily concentrated in modules #0 to #9, identified as “#0 genome wide association,” “#1 body mass index,” “#2 25 hydroxyvitamin d,” “#3 causal effect,” “#4 metabolic syndrome,” “#5 bone metabolism,” “#6 atherosclerosis,” “#7 sex hormone-binding globulin,” “#8 all-cause mortality” and “#9 genome-wide association studies,” respectively (Fig. 6). The gene discussed is SHBG; the disease is metabolic syndrome.