CD8A and neoplasm: When running correlation analysis between network PC1 (only PC among the first 3 PCs with significant association to tumor purity) and cell type estimates from CIBERSORT, we found that the top 3 correlated cell types are T cells (CD8) (ρ = − 0 . 781), Macrophages (M1) (follicular helper) (ρ = − 0 . 528), and T cells (follicular helper) (ρ = − 0 . 492).