CRP and neoplasm: While specific, real-time reimbursement rates for tumor markers like CEA, CA 19-9, PSA, CA 125, CA 15-3, and Cyfra 21-1 vary based on insurance plans and locations, generally, reimbursement for these tests is common and often covered by insurance, with costs ranging from around USD 20 to USD 105 for individual tests, with clinical chemistry markers like Ig classes, CRP, and others noted as being even less expensive.