While there has been much interest in the use of PSMA radiotracers in gliomas [15,18,19,20,22,36], our analysis demonstrated that FOLH1 showed a lack of tumor-specific expression for both adult and pediatric CNS tumors when compared to normal brain tissue, suggesting that PSMA is not a desirable target in this disease type. This evidence concerns the gene FOLH1 and central nervous system neoplasm.