Li-Fraumeni syndrome is an autosomal dominant disorder affecting one in every 500 to 20,000 individuals [1], caused by a germline mutation of tp53 coding for p53, which is often called the guardian of the genome due to its role in regulating gene damage and inducing cell cycle arrest, up to apoptosis if the damage crosses a certain threshold [2]. Here, TP53 is linked to Li-Fraumeni syndrome.