MTAP and cancer: The complete absence of associations between MTAP deficiency and parameters of aggressive disease in our 478 primary ductal pancreatic adenocarcinomas argues against the increased aggressiveness of MTAP-deficient cancer clones, although Jiang et al. [26] recently found a link between 9p21 deletion and poor prognosis in a cohort of 48 pancreatic adenosquamous cancers.