To delineate the type of BM-derived cells whose STING or IFN-I response contributes to CTX’s anti-tumor effect, we generated promoter-specific Sting1 or Ifnar1 deletion mice by crossing a mouse strain with Cre driven by the LysM, CD11c, or Xcr1 promoter to a mouse strain carrying floxed Sting1 (Sting1f/f) or Ifnar1 (Ifnar1f/f) and then used their BM cells to construct chimeras in B6 mice. Here, ITGAX is linked to neoplasm.