CRP and cholestasis: After demonstrating the potential impact of bile duct disease on miRNA levels, we investigated whether miRNA is associated with laboratory values, including C-reactive protein (CRP), as well as cholestasis markers such as alkaline phosphatase (ALP), gamma-glutamyl transferase (γGT), bilirubin, aspartate aminotransferase (ASAT), and alanine aminotransferase (ALAT) (Figure 3B).