On the other hand, the “old” PRCC type 2 is no longer a specific entity and has been broken down into several new ones, i.e., FH-deficient RCC, tubulo-cystic RCC, eosinophilic solid and cystic RCC (ESC RCC), SMARCB1-deficient medullary RCC, and RCC of the MiTF group. This evidence concerns the gene SMARCB1 and renal cell carcinoma.