In patients with ADC, low CD39 expression in tumor as well as in surrounding stroma cells correlated with a significantly higher risk of progression (HR: 2.23; 95% CI: [1.19, 4.16], p = 0.014 and HR: 3.58; 95% CI: [1.1, 11.6], p = 0.011, respectively) in the univariable analysis. Here, ENTPD1 is linked to neoplasm.