APOE and Apathy: In the MCI to ADD cohort, results of the adjusted Cox proportional-hazards model (LRT: λ(11) = 70.32, P < 0.001) revealed a 2-fold increase in conversion risk in MCI APOE ε4 carriers who endorsed apathy (HR = 2.64, 95%CI = 1.93-3.62, P < 0.001; Figure 4(A)) in comparison to the reference category of non-apathetic ε33 carriers.