NSD1 and acute myeloid leukemia: Interestingly, Carraway et al. reported the case of a patient with NUP98 fusion who relapsed after prior treatments, including allo-HSCT; the patient was treated with BMF-219 and achieved CR after a few cycles of treatment; unfortunately, after 5 months of treatment, the patient relapsed with NUP98-NSD1-positive AML [132].