For example, although ETS2-driven inflammation was not enriched in classical tumour-associated macrophages, which are typically anti-inflammatory and contribute to the immunosuppressive tumour microenvironment, some tumours are characterised by an influx of inflammatory monocyte-derived macrophages which may contribute to cancer development and spread (Caronni et al., 2023; Hill et al., 2023). Here, ETS2 is linked to neoplasm.