Indeed, neutrophils, known as the immune counterpart in which ANXA1/FPR2 colocalization was previously detected in laryngeal cancer, may be considered the main cells that secrete the protein into the tumor microenvironment, exerting anti-inflammatory/antitumoral effects in a paracrine manner through interaction with the FPR receptor [62]. This evidence concerns the gene ANXA1 and neoplasm.