In this regard, the pro-tumoral activity of G protein-coupled receptor 1 (GPR1) and CMKLR1 chemerin receptors has been recently demonstrated to induce FAAs uptake and the clear cell morphologic features in ccRCC, by modulation of tumor cells’ SREBP1c and CD36 expression [24,156]. The gene discussed is CMKLR2; the disease is nonpapillary renal cell carcinoma.