Since mTOR is so tightly connected with sensing nutrient and growth factors, it is no surprise that mTOR is activated in 60–80% of gastric cancer samples, and recently there has been genetic evidence that mTOR promotes proliferation and inhibits differentiation of gastric epithelial progenitors (GEPs) and gastric tumors [74,75]. The gene discussed is MTOR; the disease is gastric neoplasm.