Moreover, the microbiota populations in the gut also influence the DNA integrity of the host, like in the case of pathogenic mutations in the APC tumor-suppressor gene, which were more frequent in patients with bigger populations of Fusobacterium mortiferum and less frequent in patients with smaller Faecalibacterium prausnitzii and Bifidobacterium pseudocatenulatum populations [114]. The gene discussed is APC; the disease is neoplasm.