In a prospective study involving 2646 Korean adults without CKD,19 compared to serum leptin in the first tertile (male <1.69 ng/mL, female <6.08 ng/mL), serum leptin in the third tertile (male >2.91 ng/mL, female >9.89 ng/mL) was associated with an OR of 2.44 (95% CI 1.27–4.71) for incident CKD. Here, LEP is linked to chronic kidney disease.