ADGRG6 and pancreatic adenocarcinoma: Further examination of the relationship between ADGRG6 mRNA expression and clinical characteristics showed that, in the TCGA PAAD cohort, ADGRG6 was more highly expressed in younger patients and those with higher T-stage and grade (Figures 2F–H), although no significant association was observed with N-stage or chronic pancreatitis status (Supplementary Figure S1A, B).