GPT and Hepatitis: In concanavalin A-induced hepatitis mouse models, which are used widely as autoimmune hepatic disorder models, a significant increase was observed for both the plasma alanine aminotransferase (ALT) and aspartate aminotransferase (AST) for the control group, whereas a significant suppressive effect was observed in the group administered 5H8 (administration through the tail vein), which is an anti-mouse FKN monoclonal antibody [20].