Repeat testing confirmed a relapse of endogenous hypercortisolism, with a 24-hour UFC level of 1113 nmol/24 hours (403.3 μg/24 hours) and an unsuppressed serum cortisol level of 118.9 nmol/L (4.3 μg/dL) after ODST, suggesting hypercortisolemia, with an elevated ACTH level of 11.4 pmol/L (51.7 pg/mL). The gene discussed is POMC; the disease is adrenal gland hyperfunction.