Furthermore, congenital corneal opacity is attributed to biallelic mutations in SLC4A11, and dysregulation of SLC4A11 due to translocation is unlikely given the large genomic distance of the gene from the breakpoint on chr20 (~14 Mb); hence, the heterozygous variant alone was also deemed highly unlikely to be disease-causing in the proband. Here, SLC4A11 is linked to Corneal opacity.