The expression of polyamine metabolism-related enzymes, including SMOX, ODC1 and SRM, was detected by WB and qPCR experiments, and the results showed an increase in both protein and mRNA expression of SMOX, ODC1 and SRM in MDR-TB patients compared to the DS-TB group, with statistical significance by the quantitative analysis (Figure 2E-I). The gene discussed is ODC1; the disease is tuberculosis.