Table 2 shows 5 overlapping upregulated genes, ranked in order based on the Hazard ratio and p-value, including EPHX4, ANKRD22, KIF13B, TMPRSS4, and CCL28, remarkably exacerbated the OS rate of PC patients when their expression was highly exhibited (Fig. S1). Here, ANKRD22 is linked to pachyonychia congenita.