CD4 and syphilis: There were significant differences in mean CD4 cell count (2-dose series: CD4 was 560 cells/μL; 3-dose series: 470 cells/μL; P < .001), mean plasma HIV RNA load (2.5 vs 2.9 log10 copies/mL; P = .01), combination antiretroviral therapy coverage (70.0% vs 58.9%; P = .06), and syphilis coinfection (24.7% vs 14.2%; P = .03) between the arms at baseline.