NPPB and familial dilated cardiomyopathy: Each 5% annual decrease in LVEF (HR 2.066, p < 0.001), each 5 mm annual increase in LVD (HR 2.882, p < 0.001), each 5 mm annual increase in LAD (HR 2.531, p < 0.001), each 5 mm annual increase in RAD_short (HR 2.259, p = 0.002), each 5 mm annual increase in RAD_long (HR 1.938, p = 0.003), and each unit annual increase in Ln(NT-proBNP) (HR 3.366, p < 0.001) were independently associated with increased risk of all-cause mortality/HTx after adjusting for age, sex, BMI, etiology of DCM, and duration of treatment (Table 5).