LRG1 and alkaline phosphatase measurement: In fact, to further enhance the clinical utility of our work, it may also be worthwhile in future to investigate the role of LRG1-blocking antibody in other severe AP models known to induce extra-pancreatic damage (e.g., AP associated acute lung injury), such as pancreatic duct infusion of sodium taurocholate, choline-deficient diet enriched with ethionine 35 or the combination of caerulein and lipopolysaccharide 87.