PRKN and myocardial ischemia: Yang et al.72 implicate ferroptosis in diabetic myocardial ischemia/reperfusion injury via endoplasmic reticulum stress, while Chen et al.73 show that nicorandil mitigates microvascular ferroptosis through AMPK-Parkin-ACSL4—both consistent with our findings of elevated lipid peroxidation.