AF, atrial fibrillation; BID, bi-daily; CrCl, creatinine clearance; DOACs, direct oral anticoagulants; LMWH, low molecular weight heparin; NVAF, non-valvular atrial fibrillation; VTE, venous thromboembolism; Xa, factor Xa. This evidence concerns the gene TNXA and venous thromboembolism.