The receiver operating characteristic (ROC) analysis indicated that a cutoff value of 1.484 ng/mL for SESN2 provided a sensitivity of 56.7% and a specificity of 76.08% in differentiating PCOS patients from healthy controls, with an area under the curve (AUC) of 0.63 (Figure 1). This evidence concerns the gene SESN2 and polycystic ovary syndrome.