HOGA1 and atrial fibrillation: c.834G>A (35.29%), c.769T>G (17.65%), and c.834_834+1delGGinsTT (17.65%) were the three commonly observed variants of HOGA1. The c.834G>A and c.834_834+1delGGinsTT mutations cause partial and complete exon 6 skipping, respectively, with a cumulative AF of 52.94%.