Furthermore, several clinical biomarkers for PTSD, including glucocorticoid receptor [94, 95], adrenocorticotropic hormone [96, 97], neuropeptide Y [98, 99], catechol O-methyltransferase [100] and monoamine oxidase A/B have homologs in zebrafish and have been used to develop a PTSD-like model [101]. Here, POMC is linked to post-traumatic stress disorder.