These observations suggest that, even for the rare Trp53YC/YC females able to reach adulthood, the p53Y217C mutation caused pathological traits not observed in Trp53-/- females, because the loss of p53 was not previously reported to cause dystocia (Embree-Ku and Boekelheide, 2002; Guimond et al., 1996; Hu et al., 2007). This evidence concerns the gene TP53 and dystocia.