The RanBP9-TurnX mouse can be used for countless studies where it can be one “module” in compound models studying physiological functions and pathological roles that RanBP9 and the CTLH complex might have in metabolism, immune response, neurodegenerative diseases, and cancer [1, 5, 9, 10, 33, 42, 76–78]. The gene discussed is RMND5A; the disease is neurodegenerative disease.