STK11 and metabolic dysfunction-associated steatotic liver disease: Notably, Akkermansia also promote L-aspartic acid transport from the gut to the liver by upregulating L-aspartate transporter (Slc1a1 or Slc1a2) expression, thus activating the liver kinase B1 (LKB1)-AMPK axis to inhibit lipid oxidation in HFHCD-induced MASLD mice model [87].