PNPLA3 and metabolic dysfunction-associated steatotic liver disease: Latino individuals carrying the homozygous guanine (GG) genotype variant of the PNPLA3 gene (coding for triacylglycerol lipase) were more susceptible to MASLD, and the risk of developing cirrhosis in MASLD patients with GG carriers was positively associated with high sugar intake such as total sugar, fructose, sucrose, and glucose [57].