CEBPA and acute myeloid leukemia: GSEA confirmed a significant downregulation of inflammatory genes in CEBPA mutant AML (NES = –1.95, FDR = 0.003; Fig. 2a), and downregulated genes significantly overlapped those in p30-expressing HPC-7 cells (p-Val = 1.39e–15, Supplementary Fig. 2a).