SLC2A1 and Hypertension: Our data shows that in SVD, microvascular density assessed with GLUT1 may be reduced in WMH, and therewith glucose transport.30,31 Although microvascular pathology exists in WMH regardless of blood pressure status, the larger severity in not only periventricular WMH, but also in NAWM among those with hypertension may be key to the pathogenesis of SVD.