In line with global efforts to develop disease‐specific iPSC models and our longstanding interest in tauopathies, we used CRISPR/Cas9–mediated genome editing to generate iPSC lines carrying well‐characterized MAPT mutations, P301L or R406W, which are linked to FTD.59, 60, 61, 62. This evidence concerns the gene MAPT and frontotemporal dementia.