PARP1 and neoplasm: The tumor cell lines A2780cis, OVCAR-3, and OAW-42 were subjected to 24 h treatment with the IC50 concentration of each extract (according to Table 4), and the modulation of the MDR transporter protein and the apoptosis-related, cleaved form of the PARP-1 enzyme was assessed (Figure 2) with fluorescence and immune-enzymatic methods accordingly, as described.