Their research demonstrated that gavaged Quercetin (100 mg/kg) effectively prevents miscarriage by suppressing the expression of pro-inflammatory cytokines, such as IL-6 and Interleukin 8 (IL-8), while upregulating the levels of Heme Oxygenase-1 (HO-1) in peripheral blood [34]. This evidence concerns the gene HMOX1 and Miscarriage.