Furthermore, PCOS development is often linked to disruptions in key signaling pathways like Phosphoinositide 3 Kinase/Akt (PI3K/Akt), Transforming Growth Factor β/Suppressor of Mothers against Decapentaplegic (TGF-β/Smads), Wnt/β-catenin, and Hippo/YAP, which play a significant role in the disease’s progression [50]. This evidence concerns the gene AKT1 and polycystic ovary syndrome.